Throughput: 480 tests/hour 580 tests/hour with ISE
Test items on board: 36 items + ISE 3 items
Reaction volume: 120– 300 micro-liter
Patient samples on board: 72 patient samples, 30 STAT samples
Reaction volume: 140– 300 micro-liter
Test items on board: 24 items + ISE 3 items / 36 items + ISE 3 items
Patient samples on board: 30 patient samples
Throughput: 270 tests/hour 450 tests/hour with ISE
R1: 140 ～ 300μl (1μl step）
R2: 20 ～ 260μl (1μl step）
News and Announcements
Obstructive sleep apnea is a disorder in which breathing is repetitively interrupted during sleep due to collapse of the upper airway. An apnea is defined as complete cessation of breathing lasting 10 seconds or greater.
Dyslipidemia is an abnormal amount of lipids such as triglycerides, cholesterol and/or fat phospholipids in the blood. Both obstructive sleep apnea (OSA) and dyslipidemia are independent risk factors for cardiovascular disease.
An international team of investigators led by scientists at the Sahlgrenska Academy (Gothenburg, Sweden) carried out a cross‐sectional analysis that included 8,592 patients without physician‐diagnosed hyperlipidemia or reported intake of a lipid‐lowering drug (age 50.1 ± 12.7 years, 69.1% male, BMI: 30.8 ± 6.6 kg/m2, mean apnea–hypopnea index (AHI): 25.7 ± 25.9 events/hour). The independent relationship between measures of OSA (AHI, oxygen desaturation index (ODI), mean and lowest oxygen saturation) and lipid profile (total cholesterol (TC), high‐density was calculated.LabMedica
In the developing world, the manufacture and the distribution of substandard, non-legitimate medicines is widespread. It has been estimated that up to 10% of all drugs worldwide could be falsified with up to 50% of those some form of antibiotics
When a prescription is filled at the doctor"s office or pharmacy today, mostly it is taken for granted that these commonly prescribed medicines are real, and of good quality. A counterfeit or diluted antibiotic cannot only endanger an unwitting patient, but can also contribute to the wider problem of antimicrobial resistance
Biochemists at the Colorado State University (Fort Collins, CO, USA) have created a paper-based test that can quickly determine whether an antibiotic sample is appropriate strength, or diluted with filler substances like baking soda. Similar to the mechanism of a home pregnancy test, a strip of paper turns a distinctive color if a falsified antibiotic is present. The test is based on the fact that bacteria naturally produce an enzyme that can give them resistance to antibiotics by chemically binding to portions of the antibiotic molecule. The team used this very enzyme, called beta-lactamase, to empower their device to detect the presence of antibiotics in a given sample.LabMedica
Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient"s immune system is encountering for the first time.ing during gestation allows early antenatal detection and rapid treatment initiation, with economic and patient outcome benefits.
The researchers showed this in a mouse model that accurately recapitulates Duchenne muscular dystrophy. One in every 5,000 boys is born with this crippling disease, which leaves patients wheelchair-bound by mid-adolescence and is typically fatal by young adulthood. It stems from a genetic defect that deprives skeletal and cardiac muscles of a working version of a protein called dystrophin.
"Gene therapy is on the cusp of becoming a mainstream approach for treating single-gene disorders," said Lawrence Steinman, MD, professor of neurology and neurological sciences and of pediatrics at Stanford. "But there"s a catch: If you give a gene that"s a recipe for a normal protein to someone with a faulty version of the gene, whose body never made the normal protein before, that person"s immune system will mount a reaction __ in some cases, a lethal one __ to the normal protein, just as it would to any foreign protein. We think we"ve solved that problem."Read more here
Toxoplasma gondii gains access to human hosts when they eat undercooked contaminated meat or are exposed to material contaminated by feces from an acutely infected cat, which usually goes unrecognized. Vertical transmission from mother to fetus occurs from primary acute infection during gestation. Congenital infection may result in chorioretinitis, hydrocephalus, epilepsy, and death. Serologic screening during gestation allows early antenatal detection and rapid treatment initiation, with economic and patient outcome benefits.
An international team of scientists led by those at the Pritzker School of Medicine (University of Chicago, Chicago, IL, USA) collected and tested 244 samples from 205 individuals in the USA, France and Morocco. Each person of unknown serologic status underwent venipuncture, and status was confirmed either with ARCHITECT Toxo-IgG and IgM system in the Lyon, France Reference Laboratory (n = 95 persons), or for 39 Moroccan patients with Platelia Toxo IgG and IgM system.
The participants provided whole blood via fingerstick. Participants’ fingers were compressed, suffusing the tip, and cleaned with an alcohol wipe. A standard lancet was used for fingerstick. Capillary tubes allowed collection of 30 μL of blood, which was directly applied to the point-of-care (POC) Toxoplasma ICT IgG–IgM–BK test, followed by application of four drops of buffer, provided in the kit. Tests were interpreted at 20 to 30 minutes by individuals performing tests and photographed for later interpretation by two individuals unaware of the subjects’ identity and serologic status.Pritzker School of Medicine
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